Saxenda (Liraglutide)

Saxenda weight loss injection is a once-daily injectable medication designed to assist individuals on their weight loss journey. Backed by extensive clinical studies (novoMEDLINK, 2022; Clinical Trials Arena, 2023; Mehta et al, 2017), Saxenda has proven its effectiveness in helping people shed more pounds than they would through dieting alone. This weight loss treatment is tailored for adults aged 18 and above and delivers optimal results when complemented by a low-fat, reduced-calorie diet and increased physical activity (Saxenda, 2021).

Patient Information Leaflet

For more information on the prescription weight loss medication please refer to the Saxenda patient information leaflet.

Video: An overview of Saxenda

Take a look at the video below to get a simple overview of Saxenda, including what it is used for and how it works:

How does Saxenda work?

Saxenda contains Liraglutide as its active ingredient, mimicking the actions of a natural hormone called GLP-1 found in the body (Unger & Parkin, 2011). This hormone helps regulate a low blood sugar level after eating (Matsumoto et al, 2013). By replicating these effects, Saxenda assists the brain in recognizing fullness even with reduced food intake (Perone et al, 2023), ultimately reducing calorie consumption and facilitating weight loss.

How much weight can you lose by using Saxenda weight loss injection pens?

Saxenda Pen

Saxenda’s manufacturers claim that 3 out of 5 Saxenda pen users achieved substantial weight loss of at least 5% (Saxenda, 2023), which translates to an average of 12 pounds / 5.44kg.

Is Saxenda effective?

Saxenda has undergone rigorous testing for weight loss promotion and demonstrated impressive results. In a 56-week trial involving 3,731 participants, Saxenda facilitated an average weight loss of 8% of their body weight (Palmer & Apovian, 2017). Moreover, 92% of participants experienced significant weight loss when Saxenda was combined with diet and exercise (Pi-Sunyer et al, 2015).

Who should use Saxenda?

Saxenda is typically recommended for adults with a BMI (Body Mass Index) of 27 or higher, who have at least one weight-related health issue. It is always important to consult with a healthcare professional or doctor to determine if Saxenda is suitable for you.

How is a Saxenda weight loss injection pen used?

A single maintenance dose of 3mg Saxenda pen typically lasts about 6 days (Saxenda, 2023), depending on your daily dose. When not in use, store your pen in the refrigerator. Saxenda can be administered with or without food, but it’s crucial to take it at the same time every day. Many find it easier to remember by taking Saxenda with a meal, such as breakfast. You can inject it into the abdomen, thigh, or upper arm, and you can change the injection site if discomfort arises. Avoid injecting Saxenda into a vein or muscle.

How do I inject Saxenda?

Saxenda is administered as a subcutaneous injection, typically in the upper leg (thigh), stomach (abdomen), or upper arm. These are the recommended areas for injecting Saxenda.

Instructions for how to administer Saxenda injections are available in the video below that Novo Nordisk has created:

What are the side effects of Saxenda?

Saxenda Side Effects

Common side effects of Saxenda may include:

• Nausea
• Diarrhea
• Constipation
• Vomiting
• Injection site reaction
• Low blood sugar (hypoglycemia)
• Headache
• Upset stomach (dyspepsia)
• Tiredness (fatigue)
• Dizziness
• Stomach pain
• Change in enzyme (lipase) levels in your blood
• Fever*
• Gastroenteritis*

*side effects that are more commonly seen in teens, but not as common in adults.

These adverse reactions are typically mild and tend to improve over time. However, if you experience severe side effects, contact your doctor or healthcare provider immediately.

What should I do if I experience side effects?

If you experience any unusual or severe side effects while taking Saxenda, contact your healthcare provider promptly. They can assess your condition, whether it is a common side effect or a more severe case, and provide guidance on whether any adjustments to your treatment are needed.

What dosage of Saxenda should I take?

Initiating Saxenda treatment typically involves starting with a low dose and gradually increasing it over the first five weeks to reach the maximum effective dose. If you haven’t lost at least 5% of your initial body weight after 12 weeks, treatment should be discontinued. A typical dosing regimen for Saxenda can be as follows: